research Plakophilin 1 suppresses keratinocyte innate immune responses through DExD/H helicases December 2025 Plakophilin 1 helps control skin cell immune responses to prevent excessive inflammation.
research 1616 Cross-comparison of inflammatory skin disease transcriptomics identifies PTEN as a pathogenic disease classifier in cutaneous lupus erythematosus April 2023 in “Journal of Investigative Dermatology” PTEN was identified as a specific marker for the skin disease cutaneous lupus erythematosus, and it helps increase the expression of harmful type I interferons.