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research Efficacy and Tolerability of a Topical Gel Containing Mimicking Growth Factors Oligopeptides, Caffeine, Taurine and an Iron-Chelating Complex in Subjects with Androgenetic Alopecia Treated with Topical Minoxidil or Oral Finasteride: a Prospective, 6-Month, Randomized, Assessor-Blinded, 4-Arm, Parallel Group Study

December 2022 in “Clinical and experimental dermatology and therapies”

Adding the topical gel improved hair growth more than using minoxidil or finasteride alone.

research Androgenetic alopecia: may growth factor mimetic oligopeptides supplement minoxidil and finasteride therapy?

September 2023 in “Authorea (Authorea)”

Certain peptides, caffeine, taurine, and an iron complex may improve hair regrowth when used with minoxidil and finasteride for hair loss.

research Three strands ironed closely together

1 citations , January 2017 in “Science”

A new method was developed to create complex molecular knots using iron ions.

research LB1077 Cutaneous responses to systemic iron: A potential role for epidermal turnover in mammalian iron excretion

August 2019 in “Journal of Investigative Dermatology”

Skin may help in getting rid of excess iron through the process of skin cell renewal.

research Iron–Skin Axis: Exploring the Interplay between Iron Homeostasis and Skin Disorders

October 2025 in “Journal of Investigative Dermatology”

Iron balance is crucial for skin health, affecting conditions like psoriasis and hair loss.

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Community Join

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community Please take a vitamin & hormone test

in Chat 259 upvotes 1 year ago

Checking vitamin and hormone levels is important for addressing hair loss, as deficiencies in vitamin D, zinc, and iron can affect hair growth. Treatments like finasteride, minoxidil, and vitamin supplements are used, but addressing deficiencies is crucial for effectiveness.

community Dutasteride Destroying Hairline vs Just Shedding — 3 week pictures with rapid temple recession

in Finasteride/Dutasteride 23 upvotes 4 years ago

A user's experience with Dutasteride causing rapid hair loss and temple recession over 3 weeks, with other users offering advice about the potential causes of this.

community I think this is my stop, gentlepeople. So long and thanks for all the data 👋

in Transgender 2263 upvotes 1 year ago

A user shared their successful experience with hair regrowth and transitioning from male to female using minoxidil, finasteride, Nutrafol, microneedling, and hormone replacement therapy (HRT). They expressed gratitude for the results and encouraged others to explore treatments that align with their personal goals.

community The mechanism of androgenic alopecia

in Research/Science 34 upvotes 10 months ago

DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

community It’s over. NOTHING has worked.

in Chat 95 upvotes 3 years ago

A user who has been trying various treatments for hair loss for four years, with no success. Suggestions include use of minoxidil, finasteride, RU58841, microneedling, supplements and multivitamins, lifestyle changes, scalp biopsy, and SMP.

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Learn

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learn Chelating agents

learn Zinc Tri- Amino Acid complex

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Clinics

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