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      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn SCUBE3

      a signaling molecule from dermal papilla cells being actively researched

      learn KY19382

      compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

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      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  39 upvotes 3 years ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community MCL1 does anyone knows anthying about it

      in Research/Science  9 upvotes 1 year ago
      MCL-1 protein may help maintain hair follicles in the growth phase and prevent miniaturization. There is interest in experimental treatments like exosomes, peptides, or stem cell serums to upregulate MCL-1 for hair loss, especially for those not using minoxidil or finasteride.
      What NW am I? Im guessing NW 1.5?

      community What NW am I? Im guessing NW 1.5?

      in General  57 upvotes 1 year ago
      The conversation is about a user assessing their hair loss as Norwood 1.5 and discussing their use of oral minoxidil and finasteride for 2.5 years, which improved their hair density. They are content with their current progress but hope to reach Norwood 1.