research K channel therapeutics at the bedside
Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.
Search
forClinics
6 / 12 results- 22
Hair Loss TreatmentsChannell Wellness & AestheticsRancho Cucamonga, CA · US - 69Hair Loss TreatmentsTrichologyChanges ClinicPortsmouth · GB
- 17SMPChantel Benetti Dermal ClinicPretoria · ZA
- 15
Hair SystemsChangesRichfield, OH · US - 31
Hair Loss TreatmentsChanges ClinicDublin · IE - 21Hair Loss TreatmentsChanges ClinicPortsmouth · GB
Experts
4 / 4 resultsResearch
5 / 1000+ results research Effect of K+ channel openers on K+ channel in cultured human dermal papilla cells.
Increased K+ permeability alone may not promote hair growth.
research K ATP Channels and Cardiovascular Disease
K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.
research KCNQ4 K+ channels tune mechanoreceptors for normal touch sensation in mouse and man
research Immunohistochemical, pharmacovigilance, and omics analyses reveal the involvement of ATP-sensitive K+ channel subunits in cancers: role in drug–disease interactions
ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.
Community Join
5 / 306 resultscommunity Minoxidil’s mechanism of action on blood pressure as a potassium channel opening molecule
Minoxidil works by opening potassium channels, leading to reduced blood pressure and potential side effects like reflex tachycardia. It is used for hair growth and affects blood pressure at high doses.
community Creatine is the opposite of minoxidil !
Creatine may counteract minoxidil's hair growth effects by closing potassium ATP channels, potentially leading to hair loss in predisposed individuals. Despite anecdotal reports, there is no conclusive evidence linking creatine to hair loss.
community Genuine question about VDPHL01's long term safety that I haven't seen discussed here
Concerns about the long-term safety of VDPHL01, an extended-release minoxidil, due to potential risks similar to Cantu syndrome, were raised, highlighting the lack of monitoring for chronic connective tissue changes. The conversation suggests that while the treatment may improve hair growth, it could lead to issues not detected in short-term trials.
community scientific evidence of the effect of minoxidil on collagen synthesis
Minoxidil may inhibit collagen synthesis at high concentrations, with anecdotal reports of skin aging but limited research. Dermatologists and other specialists show little interest in studying minoxidil's side effects.
community The mechanism of androgenic alopecia
DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.