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Bridging Personal and Population in Excitability Diseases: Will Studies of Rare Diseases Bring Generalizable Mechanisms From Monogenic Channelopathies?

research Bridging Personal and Population in Excitability Diseases: Will Studies of Rare Diseases Bring Generalizable Mechanisms From Monogenic Channelopathies?

January 2022 in “Function”

Studying rare genetic disorders can help us understand and treat common diseases better.

research Pharmacological evidence for the involvement of adenosine triphosphate sensitive potassium channels in chloroquine-induced itch in mice

9 citations , June 2017 in “Pharmacological Reports”

ATP-sensitive potassium channels play a role in chloroquine-induced itch in mice.

Special Collection on Inward Rectifying Potassium Channels

research Special collection on inward rectifying K⁺ channels

3 citations , January 2023 in “American journal of physiology. Cell physiology”

Inward rectifier potassium channels are important in many body functions and diseases, and could be potential drug targets.

research Fibroblast bioelectric signaling drives hair growth

3 citations , August 2025 in “Cell”

Fibroblast bioelectric signaling can promote hair growth and may help treat hair loss.

research MendelVar: gene prioritization at GWAS loci using phenotypic enrichment of Mendelian disease genes

2 citations , April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

MendelVar is a tool that helps identify important genes by combining GWAS data with Mendelian disease information.

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community REVOLUTION in AUGUST: New possibilities according to Dr. Muñoz (pinacidil, cromakalim, diazoxide and nicorandil)

in Technology 13 upvotes 10 months ago

Dr. Muñoz's discovery suggests that targeting potassium channels in fibroblasts could reactivate hair growth, offering new treatment possibilities for alopecia. Potential strategies include using minoxidil, diazoxide, and other potassium channel openers, as well as bioelectric devices and direct growth factor applications.

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Hair System Specialist
Jane Genesi
Marlton, PA, United States

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Jane Genesi