research Steroid 5α-reductases and 3α-hydroxysteroid dehydrogenases: key enzymes in androgen metabolism
Key enzymes control androgen levels, affecting hormone activity and potential treatments.
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research Sebocytes are the Key Regulators of Androgen Homeostasis in Human Skin
Sebocytes play a key role in controlling androgen levels in human skin.
research Enhancement of In Vitro Hair Shaft Elongation in Follicles Stored in Buffers That Prevent Follicle Cell Apoptosis
Storing hair follicles in special buffers with added protective substances can increase hair growth and reduce cell death.
research Human Peptidylarginine Deiminase Type III: Molecular Cloning and Nucleotide Sequence of the cDNA, Properties of the Recombinant Enzyme, and Immunohistochemical Localization in Human Skin
PAD3 plays a key role in hair and skin protein structure and may be linked to skin diseases.
research The Neurosteroidogenic Enzyme 5α-Reductase Mediates Psychotic-Like Complications of Sleep Deprivation
The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.
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5 / 1000+ resultscommunity Claim: Insulin resistance increases the enzyme that creates DHT and affects the liver's ability to control hormones
Insulin resistance may increase DHT production, contributing to hair loss, and addressing it through diet, nutrients, and natural DHT blockers like saw palmetto and pumpkin seed oil could help reverse hair loss. Some users prefer medications like finasteride for more effective results.
community You may not have the enzyme for topical minoxidil to work - a rarely talked about impact
Some people may not respond to topical minoxidil due to low SULT1A1 enzyme activity, but oral minoxidil can be effective. Tretinoin may enhance minoxidil's effectiveness, and some users prefer oral minoxidil despite side effects.
community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp
Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.
community Oral Minoxidil - The Hyper-Responder Concept
Minoxidil's effectiveness varies due to genetic differences in the SULT1A1 enzyme, affecting how well it converts to its active form, minoxidil sulfate. Hyper-responders may experience rapid hair growth and increased side effects, such as pericardial effusion, even at low doses.
community Ray Peat: Testosterone Isn’t the Culprit, Prolactin and Cortisol Drive Hair Loss (2016)
Prolactin and cortisol are identified as key factors in hair loss, with stress hormones impacting hair shedding. Finasteride and minoxidil are effective treatments, while DHT's role and individual sensitivity are significant factors.
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5 / 801 resultslearn Rosemary
herb and oil with stimulant, circulatory, anti-inflammatory and antioxidant properties
learn Thymosin Beta 4
learn Neem Oil
natural substance from Neem tree with medicinal and pesticidal properties
learn Stem Cell Factor
learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
Experts
6 / 20 results- 23SMP Specialist
Kiah
Incomplete name
Melbourne, VIC, Australia
- 69
Hair Transplant SurgeonDr. Caio Franchini, MD
Ribeirao Preto, SP, Brazil
- 85
Hair Transplant SurgeonKay Dittmann
Freiburg, Baden Wurttemberg, Germany
- 21SMP Specialist
Kaio Alves
Ribeirao Preto, SP, Brazil
- 25
Hair System SpecialistGuy Enriquez
Makati City, Philippines
- 22
Hair Transplant SurgeonDr. Guy Hawkins
Monterrey, Nuevo Leon, Mexico
Clinics
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Hair Loss TreatmentsKey Laser Institute for Cosmetic Regenerative MedicinePortland, OR · US - 28Hair SystemsKey SalonMission, KS · US
- 17
Hair SystemsKey to Beauty SalonBoca Raton, FL · US - 32Hair Loss TreatmentsSandy Key Med SpaPensacola, FL · US
- 27TrichologyCM hair SPA Parrucchieri by ci and key pisaPisa · IT