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5alpha-Reductase Inhibitors Dampen L-DOPA-Induced Dyskinesia via Normalization of Dopamine D1-Receptor Signaling Pathway and D1-D3 Receptor Interaction

research 5alpha-reductase inhibitors dampen L-DOPA-induced dyskinesia via normalization of dopamine D1-receptor signaling pathway and D1-D3 receptor interaction

26 citations , September 2018 in “Neurobiology of Disease”

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

research Pregnenolone for the treatment of L-DOPA-induced dyskinesia in Parkinson's disease

2 citations , March 2023 in “Experimental neurology”

Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.

research Is seborrhea a sign of autonomic impairment in Parkinson's disease?

46 citations , November 1997 in “Journal of Neural Transmission”

Seborrhea in Parkinson's disease may be linked to hormones, not autonomic impairment.

research Effect of 5-alpha reductase inhibitors in animal models of Parkinson’s disease

September 2024 in “Frontiers in Neuroendocrinology”

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

research Le financement du cycle de l'eau en région flamande

January 2005 in “Psychoneuroendocrinology”

Finasteride may affect brain chemistry and behavior, offering potential for treating certain mental health conditions.

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Community Join

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community Has anyone with high prolactin taken meds to lower it and seen hair regrowth?

in Treatment 6 upvotes 6 months ago

High prolactin levels may contribute to hair loss, and some users suggest supplements like mucuna pruriens, vitamin B6, vitamin E, L-Tyrosine, L-Theanine, DIM, and Zinc to lower prolactin. Lifestyle changes to increase dopamine, such as reducing screen time and stress, are also recommended.

community Mucuna pruriens, dopamine and prolactin. Natural route with oils.

in Treatment 4 upvotes 3 years ago

The post discusses using Mucuna pruriens, essential oils, and dermarolling for hair loss treatment. The user also mentions pausing testosterone-boosting herbs due to side effects like acne and hair loss.

community I've been afflicted by post finasteride syndrome, what now?

in Finasteride 38 upvotes 7 years ago

A user experienced severe side effects from finasteride, including mental health issues and physical symptoms, and sought advice on managing post-finasteride syndrome. Suggestions included checking vitamin levels, considering dopamine agonists, and avoiding further psychiatric medications.

community How many are hyper responders to Finasteride?

in Finasteride/Dutasteride 5 upvotes 3 months ago

The user experienced severe side effects from finasteride, including hormonal imbalances and cognitive issues, leading to a recommendation to stop its use. They plan to follow up with tests to rule out a pituitary tumor and are considering topical treatments as alternatives.

community HMI-115 when will it be available

in Research/Science 15 upvotes 3 years ago

The potential availability of a new hair loss treatment called HMI-115, which has shown promising results in experiments on monkeys but is not yet available to the public. Replies cautioned against using unproven substances from shady labs.

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Learn

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learn L-cysteine

learn L-methionine

learn L-Lysine

learn L-Proline

learn L'Carnitine

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