research Human stratum corneum proteomics reveals cross‐linking of a broad spectrum of proteins in cornified envelopes 44 citations , March 2019 in “Experimental Dermatology” A wide range of proteins are integrated into the skin's protective layer.
research Mutations in AEC syndrome skin reveal a role for p63 in basement membrane adhesion, skin barrier integrity and hair follicle biology 33 citations , February 2012 in “British Journal of Dermatology” Mutations in the p63 gene affect skin adhesion, barrier integrity, and hair growth.
research Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function 17 citations , February 2015 in “Cell Death and Disease” Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.
research Formation of the cornified envelope 3 citations , September 2005 in “Experimental dermatology” The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.
research Characterization of sciellin, a precursor to the cornified envelope of human keratinocytes 64 citations , April 1992 in “Differentiation” Sciellin is a protein that helps form protective layers in skin, hair, and nails.