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    GlossaryHairless Gene

    gene regulating hair growth, mutations cause permanent hair loss

    The Hairless Gene, often abbreviated as HR gene, is a gene that plays a crucial role in the regulation of hair growth and development. Mutations in this gene can lead to conditions such as congenital atrichia, where individuals are born with hair that is subsequently lost and not regrown, resulting in permanent hairlessness. This gene is essential for the normal cycling of hair follicles and the maintenance of hair.

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      compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles

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      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin