The Hair Loss Encyclopedia
rare genetic disorder causing thick, plate-like skin scales
Lamellar Ichthyosis (LI) is a rare genetic skin disorder characterized by the formation of large, dark, plate-like scales over the entire body. It is caused by mutations in genes responsible for skin cell shedding and barrier function, leading to excessively thickened skin and impaired moisture retention. This condition is present from birth and requires lifelong management to alleviate symptoms and prevent complications.