research Compartmentalized organization: a common and required feature of stem cell niches? 63 citations , April 2010 in “Development” Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.
research Leucine-Rich Repeat-Containing G-Protein-Coupled Receptors as Markers of Adult Stem Cells 291 citations , April 2010 in “Gastroenterology” Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.
research Mouse Intestinal Krt15+ Crypt Cells Are Radio-Resistant and Tumor Initiating 33 citations , May 2018 in “Stem Cell Reports” Krt15+ cells in the mouse intestine resist radiation and can start tumors.
research Paneth Cells in Intestinal Homeostasis and Tissue Injury 146 citations , June 2012 in “PLoS ONE” Paneth cells help support stem cells and aid tissue regeneration after injury.
research Wnt Signaling, Lgr5, and Stem Cells in the Intestine and Skin 326 citations , February 2009 in “The American journal of pathology” Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.