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research LB1605 3D imaging of cleared ex vivo normal human skin, skin appendages and psoriasiform skin lesion using light-sheet microscopy

August 2018 in “Journal of Investigative Dermatology”

The conclusion is that using light-sheet fluorescence microscopy with a special solution can effectively create detailed 3D images of human skin for dermatological research.

research Research Techniques Made Simple: Optical Clearing and Three-Dimensional Volumetric Imaging of Skin Biopsies

2 citations , June 2020 in “Journal of Investigative Dermatology”

3D imaging of skin biopsies offers better accuracy but is time-consuming and can't clear melanin.

research Letter from the editor: Making sense of central centrifugal cicatricial alopecia

April 2024 in “Journal of the American Academy of Dermatology”

Diagnosing and treating CCCA requires understanding multiple causes and using various diagnostic tools.

Clinical and Histological Challenge in the Differential Diagnosis of Diffuse Alopecia: Female Androgenetic Alopecia, Telogen Effluvium and Alopecia Areata – Part I

research Clinical and histological challenge in the differential diagnosis of diffuse alopecia: female androgenetic alopecia, telogen effluvium and alopecia areata – part I

29 citations , October 2012 in “Anais Brasileiros De Dermatologia”

Diagnosing hair loss disorders needs clinical, dermoscopic, and histological differences, and checking menstrual cycle, weight changes, drug therapy, and nail changes.

research Polarized Versus Diffractive Microscopy in Distinguishing Scarring From Non‐Scarring Alopecia

June 2026 in “Journal of Cutaneous Pathology”

Polarized light microscopy is better at distinguishing scarring from non-scarring alopecia than diffractive microscopy.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community What do these pictures say about my hair and scalp if anything? Miniaturization, inflammation, etc.?

in Research/Science 74 upvotes 3 years ago

Hair loss and scalp issues, with people discussing possible treatments such as Nizoral shampoo, Minoxidil, neem oil, and finasteride.

community 1 Year after TE. Scarred scalp

in Progress Pictures 8 upvotes 11 months ago

Hair loss after telogen effluvium (TE) with thinning and possible scarring, treated with 5 mg oral minoxidil. Concerns about scarring alopecia and lack of regrowth, with suggestions to consider finasteride for better results.

community Dutasteride not working - is it the end?

in Finasteride/Dutasteride 2 upvotes 3 months ago

The user tried topical minoxidil, topical and oral finasteride, and switched to dutasteride and oral minoxidil without success in stopping hair loss. Suggestions included continuing treatment longer, trying microneedling, and considering a hair transplant.

community What is this pigmentation around my follicles?

in Chat 29 upvotes 1 year ago

The conversation discusses potential causes of pigmentation around hair follicles, suggesting sebum buildup, autoimmune conditions, or dermatitis. Treatments mentioned include finasteride, dutasteride, and an anti-inflammatory diet, with a recommendation to consult a doctor for a proper diagnosis.

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