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GlossaryLignans

plant-derived compounds with estrogen-like effects

Lignans are a group of chemical compounds found in plants, particularly in seeds like flaxseed, as well as in grains, vegetables, and fruits. They are phytoestrogens, meaning they can mimic or modulate the action of estrogen in the body, and have been studied for their potential health benefits, including antioxidant properties and possible roles in reducing the risk of certain cancers and cardiovascular diseases.

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Lignans and Neolignans: Plant Secondary Metabolites as a Reservoir of Biologically Active Substances

research Lignans and Neolignans: Plant secondary metabolites as a reservoir of biologically active substances

112 citations , May 2019 in “Pharmacological Research”

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Nature-Derived Lignan Compound VB-1 Exerts Hair Growth-Promoting Effects by Augmenting Wnt/β-Catenin Signaling in Human Dermal Papilla Cells

research Nature-derived lignan compound VB-1 exerts hair growth-promoting effects by augmenting Wnt/β-catenin signaling in human dermal papilla cells

17 citations , May 2018 in “PeerJ”

VB-1, a natural compound, may promote hair growth by enhancing a key cell growth pathway.

Female Breast Cancer Protection Using Phytoestrogen Lignans From Flaxseed

research FEMALE BREAST CANCER PROTECTION USING PHYTOESTROGEN LIGNANS FROM FLAXSEED

March 2026 in “International Journal of Pharmacology”

Flaxseed lignans may reduce breast cancer risk in women.

Anti-BPH Lignans From Urtica Triangularis Subsp. Pinnatifida (Hand.-Mazz.) C.J.Chen

research Anti-BPH lignans from Urtica triangularis subsp. pinnatifida (Hand.-Mazz.) C.J.Chen

December 2023 in “Natural product research”

Lignans from Urtica triangularis may help treat benign prostatic hyperplasia (BPH).

Nature-Derived Lignan Compound VB-1 Promotes Hair Growth by Augmenting Wnt/β-Catenin Signaling in Human Dermal Papilla Cells

research Peer Review #1 of "Nature-derived lignan compound VB-1 exerts hair growth-promoting effects by augmenting Wnt/β-catenin signaling in human dermal papilla cells (v0.1)"

May 2018

VB-1, a natural compound, may promote hair growth by enhancing important cell signaling and increasing key gene expression.

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