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Microscopic delivery system that sends growth-promoting signals to hair follicles
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research 878 Influence of bovine milk oligosaccharides on sebocyte lipid content and inflammatory mediators
Cow milk sugars increase fat production and inflammation in skin oil cells.
research The Ethnic Differences of the Damage of Hair and Integral Hair Lipid after Ultra Violet Radiation
Asian hair is more resistant to UV damage due to higher lipid content.
research Exogenous and endogenous lipids of human hair
Removing external lipids from hair reduces moisture and increases strength, while removing internal lipids decreases water permeability.
research Lipid loses and barrier function modifications of the brown‐to‐white hair transition
White hair has less lipid content and absorbs water differently than brown hair.
research External lipid function in ethnic hairs
African hair has the most lipids, while Caucasian hair is more hydrated and stronger.
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5 / 170 resultscommunity Napkin math: are we using 100x more topical finasteride than necessary?
Topical finasteride concentrations are likely much higher than necessary for effective follicular DHT suppression, with current standards being 100-1000 times above the theoretical minimum. Lower concentrations (0.001-0.0025%) might still work locally while minimizing systemic exposure.
community Why is dutasteride's volume of distribution so much bigger than finasteride? Is it more lipophilic and crosses barriers better?
Dutasteride has a larger volume of distribution than finasteride due to its lipophilic nature, allowing it to concentrate in hydrophobic areas and making it difficult to excrete. A user experiencing hair loss has been using oral finasteride for 10 months with minimal regrowth and is considering switching to dutasteride or adding oral minoxidil.
community Anyone experienced weight gain on dutasteride?
Dutasteride can lead to increased cholesterol and liver fat. The user is reconsidering its use due to high cholesterol and lipid levels despite a healthy lifestyle.
community Has anyone tried "The Hair Pill" from Musely?
A user ordered a compounded medication from Musely containing Dutasteride, Minoxidil, and other vitamins, expressing concerns about its contents and effectiveness. Another user shared their experience with side effects but noted hair regrowth, while adjusting the dosage to reduce symptoms.
community DHT nearly doubled after switching to oral Fin
The user switched from topical Minoxidil and Finasteride to oral Finasteride and reduced testosterone, expecting to lower DHT, but instead, DHT increased and hair loss worsened. The user is seeking advice on whether to return to the previous topical treatment or if others have experienced similar issues with oral Finasteride while on TRT.