research Lipid distribution and influence on hair structure
Lipids are crucial for maintaining hair structure and health.
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5 / 1000+ resultsresearch Discrete Nanoscale Distribution of Hair Lipids Fails to Provide Humidity Resistance
Hair lipids do not protect against humidity.
research Dihydroartemisinin loaded nanostructured lipid carriers (DHA-NLC): evaluation of pharmacokinetics and tissue distribution after intravenous administration to rats.
DHA-NLC may improve drug delivery and reduce side effects for cancer treatment.
research Integral Lipid in Human Hair Follicle
The lipid in human hair follicles acts as a barrier, similar to the skin's lipid layer.
research The hair follicle enigma
The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.
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5 / 171 resultscommunity Why is dutasteride's volume of distribution so much bigger than finasteride? Is it more lipophilic and crosses barriers better?
Dutasteride has a larger volume of distribution than finasteride due to its lipophilic nature, allowing it to concentrate in hydrophobic areas and making it difficult to excrete. A user experiencing hair loss has been using oral finasteride for 10 months with minimal regrowth and is considering switching to dutasteride or adding oral minoxidil.
community Logical reason as to why people don't get results on dutasteride?
Many users report better results with finasteride than dutasteride for hair loss, despite studies suggesting otherwise. Some suggest that dutasteride's effectiveness may depend on the delivery method, such as using lipids for absorption.
community Napkin math: are we using 100x more topical finasteride than necessary?
Topical finasteride concentrations are likely much higher than necessary for effective follicular DHT suppression, with current standards being 100-1000 times above the theoretical minimum. Lower concentrations (0.001-0.0025%) might still work locally while minimizing systemic exposure.
community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied
Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
community New and Interesting HairLoss Studies/Papers/Reviews
Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.
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6 / 10 results- 12Hair TransplantPlanet Ayurveda Distributor in DelhiNew Delhi, Delhi · IN
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Hair SystemsIvy Extension | Distributor D'extensions CapillairesSaint-Eustache, QC · CA - 9
Hair TransplantLABAID Cardiac HospitalDhaka · BD - 20
Hair Loss TreatmentsLabaid Aesthetic & Laser LoungeKafrul · BD - 20Hair Loss TreatmentsInstituto João Lobato - Tricologia, Dermatologista e NutricionistaSão Luís, MA · BR
- 26Hair Loss TreatmentsLAM+, center lepote in estetike LAM Plus, estetska klinikaLjubljana · SI
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