2 citations
,
March 2020 in “International Journal of Molecular Sciences”
Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.
The conversation discusses the potential positive effects of melatonin on hair growth. The original poster plans to try both oral and topicalmelatonin and is seeking recommendations for a good source.
A user has been using finasteride and minoxidil for hair loss but is experiencing increased shedding and is considering using topicalmelatonin with a product called Rizn. Another user is skeptical about the effectiveness of topicalmelatonin due to issues with the research and lack of replication of results, while a third user expresses interest in the outcome of using Rizn after not seeing results from topical finasteride and minoxidil.
Topicalmelatonin may help reduce hair loss and increase hair thickness in people with androgenetic alopecia (AGA), with some studies showing positive results. It can be mixed with minoxidil for application, and its effectiveness might be enhanced when used with micro-needling, but results may vary among individuals.
The conversation discusses a last-resort hair loss treatment combining topical finasteride, minoxidil, melatonin, and progesterone, with claims that topical finasteride can inhibit up to 52% of scalp DHT. One reply clarifies that progesterone is not an anti-androgen but has anti-androgenic properties because it competes with androgens for receptors.