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GlossaryLiver Function

detoxifies blood, produces bile, and synthesizes essential proteins

Liver function, also known as hepatic function, refers to the various vital processes carried out by the liver, including detoxification of harmful substances, production of bile for digestion, synthesis of proteins like albumin, and regulation of blood clotting. It is often assessed through liver function tests (LFTs), which measure levels of enzymes, proteins, and bilirubin in the blood to evaluate the liver's health and performance.

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Research

5 / 1000+ results

research A population pharmacokinetic model for individualized regimens of finasteride according to CYP3A5 genotype and liver function

October 2023 in “Journal of pharmaceutical investigation”

Finasteride dosages should be adjusted based on CYP3A5 genotype and liver function to avoid side effects.

research Liver function congruence with contraceptive medical profile in women at child-bearing ages

April 2025 in “Pharmacy Practice”

Long-term use of hormonal contraceptives may harm liver function.

research Role of S-Palmitoylation by ZDHHC13 in Mitochondrial function and Metabolism in Liver

59 citations , May 2017 in “Scientific reports”

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

research Functional and long-lived melanocytes from human pluripotent stem cells with transient ectopic expression of JMJD3

3 citations , September 2023 in “Stem Cell Research & Therapy”

Stem cells can be used to create long-lasting skin cells for treating pigment disorders.

research Glycyrrhetinic Acid Functionalized Nanoparticles for Drug Delivery to Liver Cancer

31 citations , August 2018 in “Journal of biomedical nanotechnology”

Licorice root-derived nanoparticles target liver cancer cells to improve treatment and reduce side effects.

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Community Join

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community Can liver problems be associated with response to the oral minoxidil?

in Research 147 upvotes 6 months ago

Liver problems may reduce the effectiveness of oral minoxidil due to impaired SULT1A1 enzyme activity, which is crucial for converting minoxidil to its active form. This reduction in enzyme function can significantly decrease the drug's effectiveness in promoting hair growth.

community Sensitive liver, topical fin safe to try?

in Finasteride 98 upvotes 1 year ago

Topical finasteride is considered safer for the liver than oral finasteride due to less systemic absorption, but regular liver function tests are advised. The user is concerned about liver health due to a history of NAFLD and is exploring topical finasteride as a safer alternative.

community Attention Finasteride / Dutasteride and Your liver

in Finasteride/Dutasteride 380 upvotes 1 year ago

Finasteride may cause elevated liver enzymes, potentially leading to liver issues, though this is rare. Users should monitor liver function and consider topical alternatives if liver sensitivity occurs.

community Deciding Between Oral or Topical Min and Fin with Fatty Liver

in Basic Questions 77 upvotes 1 month ago

The user is experiencing hair loss and is considering using topical minoxidil and finasteride due to concerns about liver health, specifically elevated ALT levels from fatty liver. They are advised to start with topical treatments while continuing weight loss and dietary changes to improve liver function.

community Connection between finasteride and nafld?

in Research/Science 4 upvotes 1 year ago

Finasteride may affect liver function and cortisol levels, potentially linking it to non-alcoholic fatty liver disease (NAFLD). More research is needed to understand this connection fully.

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