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research Localized Hypotrichosis Type 1 Due to Intragenic Deletion of Exons 5-8 in Desmoglein Gene in a Neonate from Indian Family

August 2023 in “Acta Scientific Paediatrics”

A baby from an Indian family had a rare genetic disorder causing no scalp or body hair due to a specific gene deletion.

research Hypertrichosis in Childhood

1 citations , April 2018 in “Turkish Journal of Dermatology”

Childhood hypertrichosis is excessive hair growth not linked to hormones, with types based on location and origin.

research More than One Gene Involved in Monilethrix: Intracellular but also Extracellular Players

35 citations , May 2006 in “Journal of Investigative Dermatology”

Monilethrix involves multiple genes affecting hair structure, including DSG4 mutations.

research Two Cases of Hypertrichosis Cubiti

2 citations , January 2007 in “Actas Dermo-Sifiliográficas”

Two cases of hairy elbows syndrome were described, with normal skin texture and symmetrical hair growth.

research Bi-allelic Mutations in LSS, Encoding Lanosterol Synthase, Cause Autosomal-Recessive Hypotrichosis Simplex

55 citations , November 2018 in “American journal of human genetics”

Mutations in the LSS gene cause a rare type of hereditary hair loss.

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community 1 month Pyrilutamide. A non responders story to everything.

in Research/Science 218 upvotes 3 years ago

My hairline, I am only 23. This conversation is about a user's experience with treatments for androgenic alopecia, including finasteride, dutasteride, RU, minoxidil, progesterone, melatonin, LLLT, oral minoxidil, and Pyrilutamide. They have tried many treatments over the course of two years without seeing much success, and they are considering getting a hair system as a last resort.

community Solving Hair Loss with Research at MIT

in Research/Science 595 upvotes 1 year ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

community 28M experiencing thinning - first timer here, please help

in Treatments 370 upvotes 7 months ago

A 28-year-old male experiencing hair thinning is considering minoxidil and finasteride. Minoxidil helps regrow hair, while finasteride prevents further loss; both are usually lifelong treatments.

community Creatine is the opposite of minoxidil !

in Research/Science 315 upvotes 9 months ago

Creatine may counteract minoxidil's hair growth effects by closing potassium ATP channels, potentially leading to hair loss in predisposed individuals. Despite anecdotal reports, there is no conclusive evidence linking creatine to hair loss.

community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

in Finasteride/Dutasteride 72 upvotes 3 years ago

Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.

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