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a JAK inhibitor for alopecia areata and other autoimmune conditions
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5 / 776 resultsresearch Impaired Hair Follicle Morphogenesis and Cycling with Abnormal Epidermal Differentiation in nackt Mice, a Cathepsin L-Deficient Mutation
Cathepsin L deficiency causes hair and skin issues in mice.
research Disruption of the temporally regulated cloaca endodermal β-catenin signaling causes anorectal malformations
Disrupting β-catenin signaling in certain cells causes anorectal malformations.
research Prediction of gain-of-function and loss-of-function mutations using Combined Annotation Dependent Depletion (CADD)
C-scores can help predict gain-of-function and loss-of-function mutations.
research PCSK9: From Nature’s Loss to Patient’s Gain
Certain genetic mutations can lower bad cholesterol and reduce heart disease risk, leading to effective cholesterol-lowering drugs.
research 457 Impact of alpha-melanocyte-stimulating hormone on mitochondrial function in human dermal fibroblasts
Alpha-MSH affects mitochondrial function, and MC1R mutations may increase skin aging.
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5 / 1000+ resultscommunity Is anyone taking creatine while on fin and/or dut?
The conversation discusses the use of creatine while on finasteride and/or dutasteride for hair loss. Opinions vary, with some users reporting no issues and others experiencing accelerated hair loss, suggesting effects are individual.
community My first 8 months and prgress so far, min + fin.
The user started experiencing hair loss at 26 and began treatment with topical minoxidil and oral finasteride. After 8 months, they noticed hair regrowth, especially baby hairs, and remain hopeful for further improvement.
community Any advice for someone starting RU?
Starting RU58841 for hair loss, with suggestions to begin with a lower dose and monitor side effects. Some users recommend sticking with finasteride, minoxidil, and dutasteride instead.
community 35M, been on Finasteride for 12 years, oral min 5mg 2 years no HT
A 35-year-old man has used finasteride for 12 years and oral minoxidil at 5 mg for 2 years, achieving significant hair regrowth and density without side effects, avoiding a hair transplant. He recommends consistency with medication and highlights the effectiveness and affordability of oral minoxidil.
community Does lowering serum prolactin lower prolactin in the scalp?
The conversation discusses whether not masturbating (semen retention) affects hair loss, with opinions varying but generally dismissing the idea. Some participants mention using hair loss treatments like Minoxidil, Finasteride, and RU58841, but the effectiveness and relation to prolactin levels in the scalp are debated.