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GlossaryLong QT Syndrome

heart rhythm disorder causing prolonged QT interval on ECG

Long QT Syndrome (LQTS) is a heart rhythm disorder that can cause fast, chaotic heartbeats, potentially leading to fainting, seizures, or sudden death. It is characterized by an abnormally prolonged QT interval on an electrocardiogram (ECG), which indicates delayed repolarization of the heart after a heartbeat. This condition can be inherited or acquired and may be triggered by certain medications, electrolyte imbalances, or other medical conditions.

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Clinical Characterization of Men with Long QT Syndrome and Torsades de Pointes Associated with Hypogonadism: A Review and Pharmacovigilance Study

research Clinical characterization of men with long QT syndrome and torsades de pointes associated with hypogonadism: A review and pharmacovigilance study

17 citations , August 2019 in “Archives of Cardiovascular Diseases”

Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.

research Androgenic Effects on Ventricular Repolarization

64 citations , August 2019 in “Circulation”

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

research Hypogonadism as a Reversible Cause of Torsades de Pointes in Men

60 citations , July 2018 in “Circulation”

Low testosterone can cause a heart rhythm problem in men, but fixing it can prevent the issue.

Androgenic Effects on Ventricular Repolarization: A Translational Study from Pharmacovigilance Databases to iPSC-Cardiomyocytes

research P6590Androgenic effects on ventricular repolarization: a translational study from pharmacovigilance databases to iPSC-cardiomyocytes

October 2019 in “European heart journal”

Androgen-deprivation therapies increase the risk of certain heart conditions, but testosterone treatment may help.

research Index of Suspicion

November 2007 in “Pediatrics in review”

A boy with long QT syndrome was treated successfully, highlighting the need for careful evaluation of chest pain in children for heart conditions like LQTS.

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community Is there a consensus on RU these days? Pyril turned out to be a bust right?

in Research/Science 17 upvotes 2 years ago

The conversation discusses the effectiveness and safety of hair loss treatments, specifically RU58841 and Pyrilutimide (Pyril), with users sharing that Pyril was no more effective than a placebo and expressing concerns about the safety of RU58841 based on personal experiences and the lack of pharmaceutical interest.

community This sub in a nutshell when it comes to medicine. Oral Minoxidil isn’t that bad

in Chat 446 upvotes 3 years ago

The post and conversation are about the use of oral Minoxidil (Min), Finasteride (Fin), and RU58841 for hair loss treatment, with mixed opinions on their safety and effectiveness.

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