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GlossaryLichen Planopilaris (LPP)

rare inflammatory condition causing scarring and permanent hair loss

Lichen Planopilaris (LPP) is a rare inflammatory condition that affects the hair follicles, leading to scarring and permanent hair loss. It is a form of lichen planus that specifically targets the scalp, causing symptoms such as redness, itching, and scaling. Early diagnosis and treatment are crucial to prevent extensive hair loss.

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research Prevalence of Hormonal and Endocrine Dysfunction in Patients with Lichen Planopilaris: A Retrospective Data Analysis of 168 Patients

44 citations , February 2017 in “Journal of the American Academy of Dermatology”

Lichen planopilaris (LPP) is linked to androgen excess, while frontal fibrosing alopecia (FFA) is linked to androgen deficiency.

Reply to ‘CD123 Immunohistochemistry for Plasmacytoid Dendritic Cells Is Useful in the Diagnosis of Scarring Alopecia’: Three PDC-Related Parameters Are Useful in Differentiating Lupus Alopecia from LPP

research Reply to ‘CD123 Immunohistochemistry for Plasmacytoid Dendritic Cells Is Useful in the Diagnosis of Scarring Alopecia’: Three PDC-Related Parameters Are Useful in Differentiating Lupus Alopecia from LPP

4 citations , November 2016 in “Journal of Cutaneous Pathology”

Three characteristics of plasmacytoid dendritic cells help tell apart lupus-related hair loss from LPP.

research Lichen Planus Pigmentosus and Lichen Planus Pigmentosus: 35 Cases in Armenia, Colombia

1 citations , May 2015 in “Journal of The American Academy of Dermatology”

Lichen planus pigmentosus and fibrosing frontal alopecia in Colombia are likely different stages of the same disease.

research Evaluation of Hair Surface Structure and Morphology of Patients with Lichen Planopilaris by Atomic Force Microscopy

September 2024 in “Skin Research and Technology”

AFM can help diagnose lichen planopilaris by identifying specific hair structure changes.

research Therapeutic Intervention in Lichen Planus Pilaris: Synergy of Low-Level Laser Therapy and Topical Corticosteroid

January 2024 in “Brazilian Journal of Hair Health”

Combining low-level laser therapy with topical corticosteroids effectively improved Lichen Planopilaris symptoms.

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community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 49 upvotes 1 year ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Anyone with LPP have regrowth with Xeljanz?

in Treatment 3 upvotes 1 year ago

The conversation is about using Xeljanz for hair regrowth in individuals with LPP. The user is seeking experiences and expectations from others who have tried this treatment.

community mallia therapeutics 8T3 scd83 molecule for ffa/lpp mainly and aga

in Technology 7 upvotes 2 weeks ago

A user applied the 8T3 product for hair loss, targeting LPP and AGA, and plans to update on its effectiveness. The product uses a saline buffered phosphate vehicle, suitable for those intolerant to ethanolic vehicles.

community Losing Hair on Dutasteride? You might have LPP

in Research/Science 98 upvotes 11 months ago

Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.

community Hair Loss & Lipids: Why you have sebderm, folliculitis, LPP, inflammation, etc...

in Research/Science 133 upvotes 10 months ago

Excess sebum rich in cholesterol and triglycerides can lead to hair loss through inflammation, with treatments like Ciclopirox shampoo, Benzoyl Peroxide shampoo, and Clindamycin gel recommended for managing conditions like seborrheic dermatitis and folliculitis. Pioglitazone is suggested for Lichen Planopilaris, while Omega-3s and reducing processed foods may improve sebum quality, though genetic factors play a significant role.

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