research 1359 Hair growth is induced by blockade of macrophage-derived oncostatin M and downstream JAK-STAT5 signaling in hair follicle stem cells
Blocking a specific immune cell signal can trigger hair growth.
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research The local hypothalamic–pituitary–adrenal axis in cultured human dermal papilla cells
Stress hormone CRF can cause hair loss by affecting hair growth cells and hormones.
research Compendium of polycystic ovarian syndrome and its relevance in glycation and diabetes
PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.
research Author response: Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin
ERK activation spreads between cells, influencing cell division and wound healing.
research FGF18 signaling determines radioresistance of telogen hair follicles by the arrest of hair cycling
FGF18 helps hair follicles resist radiation by stopping hair growth cycles.
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5 / 1000+ resultscommunity Having androgen receptor density and sensitivity at wrong f*ing place
The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.
community Oral Minoxidil & Coffee – Any issues due to adenosine receptor blockade?
Oral Minoxidil users discuss whether caffeine affects its effectiveness due to adenosine receptor blockade. Users report no significant impact on hair growth despite caffeine consumption.
community Has anyone powered through the creatine shedding (via increased androgen receptor sensitivity) and stabilized?
Creatine may cause increased hair shedding due to androgen receptor sensitivity, despite limited evidence. The user is using dutasteride and minoxidil and seeks advice on whether shedding will stabilize, with suggestions including GHK-Cu and RU58841.
community Is regrowth on an androgen receptor blocker possible?
RU and Pyri block androgen receptors to prevent hair loss but may also hinder hair regrowth since they prevent testosterone, which can stimulate hair growth, from binding to these receptors. The user is questioning if this understanding is correct.
community I’m considering stopping finasteride
The user is considering stopping finasteride due to depression, anxiety, and difficulty building muscle, despite its effectiveness in stopping hair loss. Suggestions include reducing the dose, switching to topical solutions, or consulting a doctor for alternatives like dutasteride or RU58841.
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