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      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

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      technique to inject very small amounts of beneficial chemicals into the scalp

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      a JAK inhibitor for alopecia areata and other autoimmune conditions

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      community 22 years since the last major development

      in Technology  51 upvotes 4 years ago
      The conversation discusses the lack of significant advancements in hair loss treatments since the introduction of finasteride 22 years ago, with many expressing frustration over the failure of new projects and skepticism about future developments. Some users mention hair transplants and other potential alternatives like Alfatradiol and Fluridil, but acknowledge finasteride's dominance in the market due to its effectiveness and affordability.

      community I have been battling hair loss for 20 years, feel free to ask me anything

      in Progress Pictures  150 upvotes 3 years ago
      A user's 20 year journey with hair loss and the treatments they have used to manage it, including finasteride, minoxidil, a custom Strut Blend of Dutasteride, Minoxidil, Tretinoin, and Biotin, Nizoral shampoo, multivitamins, Vitamin D, B Complex, Dim, Clomid, exercise, diet, laser helmet, Toppik dark brown, and topical Finasteride. The user also talks about their successful life, lack of desire for children and high sperm count due to Clomid.