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GlossaryMacrofibrils

large structural components within hair fibers, enhancing strength and elasticity

Macrofibrils are large, structural components found within hair fibers, composed of smaller units called microfibrils. These macrofibrils contribute to the strength and elasticity of hair, playing a crucial role in its overall integrity and resilience.

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Research

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research Organization of microfibrils in keratin fibers studied by X-ray scattering

63 citations , December 1998 in “Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology”

The study improved understanding of keratin fiber structure by showing consistent microfibril diameter but varying distances and electron density profiles.

research Three-dimensional architecture of macrofibrils in the human scalp hair cortex

55 citations , February 2014 in “Journal of Structural Biology”

Human hair has a complex, variable structure with a consistent matrix and double-twist pattern.

research Nucleation and growth of macrofibrils in trichocyte (hard-α) keratins

24 citations , June 2003 in “Journal of Structural Biology”

Sheet formation is key to macrofibril structure differences in wool.

research Helical twist direction in the macrofibrils of keratin fibres is left handed

9 citations , April 2019 in “Journal of Structural Biology”

Keratin fibers in hair twist left-handed.

research Macrofibril Formation

6 citations , January 2018 in “Advances in experimental medicine and biology”

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community Here is my hair regrowth plan

in Treatment 4 upvotes 5 years ago

The user's hair regrowth plan includes topical treatments (RU58841, azelaic acid, ketoconazole), oral supplements (Gia Herbs, castor oil), microneedling, PTD-DBM peptide with valproic acid, red light therapy, inversion table with scalp massage, and platelet-rich fibrin injections. Commenters suggest that finasteride and minoxidil are essential treatments for male pattern hair loss, which are missing from the plan.

community Fin for 7 months and my sclap is now transparent

in Progress Pictures 16 upvotes 5 months ago

A 24-year-old male has been using finasteride for 7 months and noticed thinning hair, especially when wet, and is concerned about the effectiveness of the treatment. Suggestions include continuing finasteride, considering minoxidil, and possibly trying micro-needling.

community Difference between my hair wet and dry literally an hour apart

in Finasteride/Dutasteride 757 upvotes 1 year ago

The conversation is about hair loss treatments, focusing on minoxidil and finasteride, with suggestions for microneedling and dermarolling to improve hair thickness. The original poster has used minoxidil for four years and finasteride for over a year but is exploring additional options for better results.

community The Biggest Concern That I Have For Oral Minoxidil: Cardiac Hypertrophy

in Minoxidil 27 upvotes 3 years ago

Oral minoxidil can cause serious heart issues like cardiac hypertrophy and arrhythmias, prompting some users to reduce dosage or switch to topical treatments. Despite significant hair regrowth, side effects such as shortness of breath and chest pains are common concerns.

community 12 months of progress on fin (and 10 months microneedling)

in Update 364 upvotes 7 years ago

A user's 12 month progress on finasteride and 10 months of microneedling for hair loss treatment, which has resulted in improved temple areas with no side effects from the finasteride. They have not used minoxidil yet but are considering it for further gains. DHT blocking drugs such as finasteride and dutasteride are recommended to maintain regrowth results.

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