research Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis 293 citations , September 2004 in “Development” WNT signaling is crucial for starting mammary gland development.
research Sostdc1 defines the size and number of skin appendage placodes 56 citations , February 2012 in “Developmental biology” Sostdc1 controls the size and number of hair and mammary gland structures.
research HOXC8 initiates an ectopic mammary program by regulating Fgf10 and Tbx3 expression, and Wnt/β-catenin signaling 19 citations , January 2015 in “Development” Hoxc8 gene helps start mammary gland development by controlling specific signals.
research Genetic basis of skin appendage development 111 citations , January 2007 in “Seminars in cell & developmental biology” Hair, teeth, and mammary glands develop similarly at first but use different genes later.
research Identification of dkk4 as a target of Eda-A1/Edar pathway reveals an unexpected role of ectodysplasin as inhibitor of Wnt signalling in ectodermal placodes 117 citations , April 2008 in “Developmental biology” Ectodysplasin inhibits Wnt signaling to help form hair follicles.