research Surface Lipids as Multifunctional Mediators of Skin Responses to Environmental Stimuli 105 citations , January 2010 in “Mediators of Inflammation” Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.
research Mediators of Inflammation in Polycystic Ovary Syndrome in Relation to Adiposity 102 citations , January 2010 in “Mediators of Inflammation” PCOS is linked to obesity and inflammation, increasing cardiovascular risk.
research Mediator1: An Important Intermediary of Vitamin D Receptor–Regulated Epidermal Function and Hair Follicle Biology 5 citations , March 2012 in “Journal of Investigative Dermatology” Vitamin D receptor and mediator 1 are crucial for healthy skin and hair growth.
research Mediator 1 ablation induces enamel-to-hair lineage conversion in mice through enhancer dynamics 1 citations , July 2023 in “Communications biology” Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.
research Mediator 1 ablation induces enamel-to-hair lineage conversion through enhancer dynamics September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Removing Mediator 1 causes teeth cells to turn into hair cells.
community [Nov 2019] The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression 22 upvotes 6 years ago A peptide from Japanese water chestnut fruit may help with hair loss by suppressing DHT's effect on hair follicle cell death, potentially serving as a finasteride alternative. The treatment's effectiveness and safety in humans remain uncertain.