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GlossaryMelanin Granules

tiny particles in cells that determine hair and skin color

Melanin granules, also known as melanin pigments, are tiny particles produced by specialized cells called melanocytes. These granules are responsible for the coloration of skin, hair, and eyes by absorbing and scattering light. The amount and type of melanin granules determine an individual's pigmentation, playing a crucial role in protecting the skin from UV radiation.

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research In-Situ Imaging Mass Spectrometry Analysis of Melanin Granules in the Human Hair Shaft

50 citations , February 2004 in “Journal of Investigative Dermatology”

Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity

research Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity

July 2023

The human scalp has different types of pigment cells in hair follicles with varying abilities to produce pigment.

The Silver Locus Product (Silv/gp100/Pmel17) as a New Tool for the Analysis of Melanosome Transfer in Human Melanocyte–Keratinocyte Co-Culture

research The silver locus product (Silv/gp100/Pmel17) as a new tool for the analysis of melanosome transfer in human melanocyte–keratinocyte co‐culture

68 citations , March 2008 in “Experimental dermatology”

The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.

A Discourse on Human Hair Fibers and Reflections on the Conservation of Drug Molecules

research A discourse on human hair fibers and reflections on the conservation of drug molecules

47 citations , June 1996 in “International Journal of Legal Medicine”

Hair analysis for drugs needs a better understanding of how drugs enter hair, considering factors like hair structure and pigmentation.

research Hair Follicular Expression and Function of Group X Secreted Phospholipase A2 in Mouse Skin

35 citations , January 2011 in “Journal of Biological Chemistry”

sPLA2-X is crucial for normal hair growth and follicle health.

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