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Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition

research Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition

174 citations , November 2016 in “Cell stem cell”

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Comparison of Mesenchymal Progenitor Cell Coating on MBA and DBM as Biochemical Scaffolds

research The comparison of the mesenchymal progenitor cell coating state on the MBA and DBM as the biochemical scaffolds

September 2011 in “Clinical Biochemistry”

The demineralized bone matrix scaffold is better for cell attachment than the mineralized bone allograft.

research Hdac1 and Hdac2 regulate the quiescent state and survival of hair-follicle mesenchymal niche

1 citations , August 2023 in “Nature communications”

Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.

research 1376 A multi-scale spatial atlas of human skin links cancer cell states to site of origin

April 2023 in “Journal of Investigative Dermatology”

The research shows that skin cancer likely originates from hair follicles and that certain cell populations expand to promote skin cancer growth.

research Multimodal Human Scalp Atlas Defines Cell Landscape and Lineage Architecture In Situ

June 2026 in “bioRxiv (Cold Spring Harbor Laboratory)”

The atlas maps human scalp cells, revealing insights into hair loss and potential treatments.

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Community Join

5 / 25 results

community Hair cloning breakthrough, this might just be the big one ?

in Research/Science 426 upvotes 5 months ago

Japanese scientists discovered ABM cells, enabling successful human hair follicle cloning, potentially curing hair loss. The treatment may be available in Japan by 2028, but it will be expensive and require travel.

community Exosomes - do they work as results look promising?

in Treatment 3 upvotes 6 years ago

Exosomes are being considered for hair regrowth, with some users reporting initial improvement. One user moved on to using dutasteride and oral minoxidil with positive results.

community DHT Isn’t the Only Factor in Hair Loss and That Might Be the Key to a Real Cure

in Research/Science 372 upvotes 5 months ago

Hair loss involves more than just DHT, with genetic factors like TRPS affecting hair follicles. Treatments such as Amplifica's AMP-601 and AMP-303 target stem cells for potential hair growth solutions.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 678 upvotes 1 year ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Finasteride only reduces scalp DHT by ~40%. Why does it work?

in Finasteride/Dutasteride 37 upvotes 3 years ago

How Finasteride and Dutasteride help reduce hair loss by reducing the amount of DHT in scalp areas, as well as discussing factors such as sensitivity to DHT, 5α-reductase expression in different parts of the hair follicle, and scalp tension.

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Learn

4 / 801 results

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Overview

learn Epidermal Growth Factor

learn Stem Cell Factor

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Experts

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SMP Specialist
Małgosia Zawadzka
Poznań, Poland

Clinics

6 / 16 results

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Małgosia Zawadzka