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GlossaryMetabolomics

study of small molecules in biological systems

Metabolomics is the scientific study of the unique chemical fingerprints left behind by specific cellular processes, focusing on the small molecules, or metabolites, within cells, tissues, or organisms. It provides a comprehensive snapshot of the metabolic state and can be used to understand disease mechanisms, including those related to hair loss and alopecia, by analyzing changes in metabolic profiles.

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The Prevalence of Metabolic Disorders in Various Phenotypes of Polycystic Ovary Syndrome: A Community-Based Study in Southwest Iran

research The prevalence of metabolic disorders in various phenotypes of polycystic ovary syndrome: a community based study in Southwest of Iran

53 citations , September 2014 in “Reproductive Biology and Endocrinology”

Different types of PCOS have different levels of metabolic problems, with the most severe type showing the highest disturbances.

research Metabolomic biomarkers in women with polycystic ovary syndrome: a pilot study

43 citations , July 2012 in “Molecular human reproduction”

Certain metabolites are lower in women with PCOS and could be potential markers for the condition.

research Metabolomic analysis of amino acids and lipids in human hair altered by dyeing, perming and bleaching

24 citations , April 2016 in “Experimental Dermatology”

Chemical treatments like dyeing, perming, and bleaching damage hair by altering amino acids and lipids.

Metabolic and Transcriptomic Reprogramming During Contact Inhibition-Induced Quiescence Is Mediated by YAP-Dependent and YAP-Independent Mechanisms

research Metabolic and transcriptomic reprogramming during contact inhibition-induced quiescence is mediated by YAP-dependent and YAP-independent mechanisms

11 citations , August 2024 in “Nature Communications”

Quiescent cells have increased mitochondrial activity and ECM gene expression, but reduced glycolysis.

research How storage post sampling influences the stability of sebum when used for mass spectrometry metabolomics analysis?

7 citations , September 2024 in “Scientific Reports”

Sebum samples remain stable under various storage conditions, making them suitable for remote and at-home testing.

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community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.

in Research/Science 2 upvotes 1 year ago

A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.

Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

in Research 413 upvotes 1 year ago

Treating androgenic alopecia with minoxidil, finasteride, and antiandrogens, alongside exercise, cryotherapy, and natural substances to stimulate cold receptors for better hair growth. The method focuses on enhancing treatment effectiveness by considering environmental and behavioral factors and the role of cold receptors and muscle stress.

community Physio-metabolic method (antiandrogen, minoxidil, leg training and cold)

in Treatments 309 upvotes 2 years ago

The method combines finasteride, minoxidil, intense leg exercises, and cold exposure to treat androgenetic alopecia. It aims to boost metabolism and reduce androgenic effects, enhancing hair growth.

community Adipocyte lipolysis activates epithelial stem cells for hair regeneration through fatty acid metabolic signaling

in Research/Science 22 upvotes 9 months ago

Fatty acid metabolic signaling can activate epithelial stem cells for hair regeneration. Oleic and palmitoleic acids showed the best results, but practical application on humans remains uncertain.

community Debunking the "Adverse metabolic consequences of dutasteride"

in Research/Science 44 upvotes 5 years ago

Dutasteride is more effective than finasteride, has neuroprotective benefits, and may prevent acne. Despite initial concerns about metabolic effects, further research suggests it is safe for most users, especially if not hypogonadal.

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