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research Defects in mitochondrial DNA replication and oxidative damage in muscle of mtDNA mutator mice

53 citations , October 2014 in “Free radical biology & medicine”

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

research 1368 Does mitochondrial dysfunction drive immune privilege collapse in lichen planopilaris pathogenesis?

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

Mitochondrial dysfunction may contribute to chronic inflammation and immune system issues in Lichen planopilaris.

Issue Information: Overview of Studies in Clinical and Experimental Dermatology

research Issue Information

September 2017 in “Clinical and Experimental Dermatology”

The document summarized various dermatology studies and case reports.

research Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients

198 citations , June 2013 in “Molecular psychiatry”

Schizophrenia patients' stem cells show abnormal neuron development and mitochondrial issues.

A NIR-Responsive PDA@RES Core-Shell Nanoplatform Accelerates Chronic Wound Healing by Remodeling Mitochondrial Homeostasis and Reversing Cellular Senescence

research A NIR-responsive PDA@RES core-shell nanoplatform accelerates chronic wound healing by remodeling mitochondrial homeostasis and reversing cellular senescence

February 2026 in “Nano Research”

A special treatment speeds up chronic wound healing by fixing cell energy issues and reversing aging in cells.

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Community Join

5 / 110 results

community Could fatty liver(other issues related to it..)play a role in Dupa/Aga?

in Treatment 5 upvotes 1 year ago

Fatty liver and related issues may influence hair loss conditions like Dupa/Aga. Treatments discussed include Minoxidil, finasteride, RU58841, myo-inositol, and L-glutamine.

community The mechanism of androgenic alopecia

in Research/Science 34 upvotes 10 months ago

DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 97 upvotes 6 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community Lost 65% of hair last 3 years. No regrowth. Also have Seborrheic Dermatitis flare ups. Diagnosed by derm as "alopecia". Started taking 2 supplements I researched and 0 flare up for over 2 months. New hair growing. Scalp healthy. Everything else has stayed the same! Overjoyed is an understatement!!

in Treatment 18 upvotes 3 years ago

After suffering from hair loss and Seborrheic Dermatitis for three years with no improvement from various treatments, the individual found success with COQ10 and PQQ supplements, which led to new hair growth and a healthy scalp without flare-ups. They also plan to start additional supplements recommended by a dermatologist.

community If PP405 goes systemic this would be quite catastrophic

in Research/Science 4 upvotes 1 year ago

Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.

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