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      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn Ketoconazole

      antifungal with some anti-androgenic benefits, often used as a shampoo

      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

      learn Alfatradiol

      a synthetic estrogen used topically as an anti-androgen

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      community Average r/bald user complaining

      in Satire  400 upvotes 3 weeks ago
      Hair loss treatments like Minoxidil, finasteride, and RU58841, focusing on their effectiveness and side effects. It also highlights the disparity in medical research funding between hair loss and conditions like endometriosis.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  135 upvotes 1 year ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community 4 months finasteride + minoxidil combo spray

      in Progress Pictures  487 upvotes 8 months ago
      The user has been using a finasteride and minoxidil combo spray from Hims for four months, with positive results and no side effects. They apply four sprays nightly, targeting the crown and front of the scalp.

      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

      in Research/Science  126 upvotes 2 years ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

      community Rate my Hair loss prevention stack

      in Treatment  4 upvotes 1 week ago
      The user is using a comprehensive hair loss prevention regimen including Dutasteride, RU58841, topical treatments, red light therapy, microneedling, and supplements like Nutrafol, while avoiding Minoxidil. They also supplement with vitamin D and zinc and plan to start testosterone replacement therapy (TRT) in January.