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GlossaryMultipotent Stem Cells

can develop into multiple, but limited, cell types

Multipotent stem cells are a type of stem cell that can develop into multiple, but limited, cell types within a particular tissue or organ. For example, hematopoietic stem cells in the bone marrow can differentiate into various types of blood cells, but not into cells of other tissues like neurons or muscle cells. These cells are crucial for tissue repair and regeneration, making them a significant focus in medical research and therapies.

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research Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin

555 citations , July 2001 in “Genes & Development”

Tcf3 and Lef1 are key in deciding skin stem cell roles.

research Thymic epithelial cells : relatives of multipotent stem cells of the skin

January 2008 in “Infoscience (Ecole Polytechnique Fédérale de Lausanne)”

Thymic epithelial cells may be related to skin stem cells.

research Microenvironmental reprogramming of thymic epithelial cells to skin multipotent stem cells

116 citations , August 2010 in “Nature”

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

research Multipotent Nestin-Positive Stem Cells Reside in the Stroma of Human Eccrine and Apocrine Sweat Glands and Can Be Propagated Robustly In Vitro

33 citations , October 2013 in “PloS one”

Human sweat glands have a type of stem cell that can grow well and turn into different cell types.

Human Skin Stem Cells and the Aging Process

research Human skin stem cells and the ageing process

143 citations , September 2008 in “Experimental gerontology”

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

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community Microneedling and aloe vera to recruit stem cells.

in Chat 11 upvotes 2 years ago

Microneedling combined with aloe vera may stimulate dormant stem cells in hair loss areas. Minoxidil is also suggested for better results.

community Hair and normal skin created from human pluripotent stem cells for the first time

in Update 86 upvotes 6 years ago

Human pluripotent stem cells have been used to create hair and skin, potentially offering a new solution for baldness. A user also mentioned starting finasteride but experiencing unexpected hair thinning.

community Functional hair follicles grown from stem cells: Scientists have created natural-looking hair that grows through the skin using human induced pluripotent stem cells (iPSCs), a major scientific achievement that could revolutionize the hair growth industry.

168 upvotes 7 years ago

Scientists have grown natural-looking hair from stem cells, potentially revolutionizing hair growth treatments. Concerns include cost, DHT resistance, and the need for future procedures.

community Anyone here have a lot of knowledge on hair follicle stem cells and progenitor cells for PP405?

in Chat 4 upvotes 6 months ago

Hair follicle stem cells remain in bald individuals, but progenitor cells do not, raising questions about hair regrowth claims by Pelage. PP405 is discussed as a potential treatment, with skepticism about its effectiveness compared to existing treatments like Minoxidil and Finasteride.

community "Hair Follicle Stem Cells are quiescent 99% of the time and permanently reside in the hair follicle"

in Research/Science 1391 upvotes 10 months ago

Hair follicles are mostly dormant but can be reactivated with treatments like minoxidil, finasteride, and microneedling. A new drug, PP405, shows promise for hair regrowth but may not be available until 2027-2028.

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