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GlossaryNail Psoriasis

condition where psoriasis affects fingernails and toenails, causing pitting

Nail psoriasis, also known as psoriatic nail disease, is a condition where psoriasis affects the fingernails and toenails. It can cause a variety of symptoms, including pitting (small dents) in the nails, discoloration, thickening, and separation of the nail from the nail bed (onycholysis). This condition is often associated with psoriatic arthritis and can significantly impact nail appearance and function.

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Research

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research 151 High effectiveness of tildrakizumab over 52 weeks in patients with or without nail psoriasis: results from the phase IV POSITIVE Austrian subset

November 2024 in “Journal of Investigative Dermatology”

Tildrakizumab significantly improved psoriasis symptoms and well-being over 52 weeks.

research From the Cochrane Library: Interventions for Nail Psoriasis

March 2025 in “Dermatology”

Systemic therapies improve nail psoriasis but have high side effects; more research is needed.

research Videodermoscopy of the hyponychium in nail bed psoriasis

76 citations , March 2008 in “Journal of the American Academy of Dermatology”

Videodermoscopy can help diagnose and monitor nail bed psoriasis.

research Interventions for nail psoriasis

65 citations , January 2013 in “Cochrane library”

Some systemic treatments work for nail psoriasis but can have serious side effects.

research Case of de novo nail psoriasis triggered by the second dose of Pfizer-BioNTech BNT162b2 COVID-19 messenger RNA vaccine

28 citations , September 2021 in “JAAD Case Reports”

The Pfizer COVID-19 vaccine may rarely trigger nail psoriasis.

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community Losing a ton consistently after 8 months dut please help me I don’t know what to do anymore, nothing works

in Chat 76 upvotes 1 year ago

A 20-year-old is experiencing hair loss despite using dutasteride and oral minoxidil. Suggestions include consulting a specialist, considering RU58841, and checking for other conditions and vitamin deficiencies.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

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