research NEDD4 and NEDD4L Regulate Wnt Signaling and Intestinal Stem Cell Priming by Degrading LGR5 Receptor
NEDD4 and NEDD4L help control intestinal stem cells and prevent tumors by breaking down the LGR5 receptor.
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research Comparative Ubiquitinomics of Human Skin Reveals Insulin Receptor Ubiquitination as a Regulator of Collagen Secretion
Ubiquitination of the insulin receptor regulates collagen secretion in human skin.
research Erasing the Methyl Mark: Histone Demethylases at the Center of Cellular Differentiation and Disease
Histone demethylases can change gene expression and may be linked to diseases like cancer.
research Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
research Foxp3 Post-Translational Modifications and Treg Suppressive Activity
Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.
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5 / 6 resultscommunity Post Finasteride Syndrome, A dangerous lie.
A user initially had side effects from finasteride, attributed them to anxiety and the nocebo effect, and after resuming the drug, experienced positive effects and now warns against misinformation about Post Finasteride Syndrome.
community Should I dedicate my university studies to solving hair loss?
A 20 year old male who is balding and considering switching to a biology/chemistry program in order to find a low-cost, accessible solution for hair loss. Replies discuss the merits of this idea as well as potential treatments such as Minoxidil, finasteride, RU58841, TM5614, and ADQ.
community A New Therapeutic Channel to Come Soon: Hair Follicle Sugar Metabolism and Aldose Reductase
Hair loss therapies focusing on hair follicle sugar metabolism and aldose reductase. Potential treatments include magnesium supplements, avoiding high glycemic index foods, and antioxidants.
community Progress- 3 months, 5% Minoxidil, 0.1% Finasteride
The user experienced significant hair loss after stopping a treatment of 5% Minoxidil and 0.1% Finasteride, which they had used from December 2021 to January 2024. They resumed the treatment in April 2025, hoping for regrowth, and are considering additional treatments like transplants and steroid injections.
community 5 month progress Fin 1mg and topical min 5%
A user reported impressive hair regrowth after 5 months using finasteride 1mg daily, topical minoxidil 5% twice a day, and microneedling. They initially experienced shedding but now have minimal hair loss and no sexual side effects.