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GlossaryNeurotoxicity

damage to nervous system cells by toxic substances

Neurotoxicity refers to damage to the nervous system caused by exposure to natural or artificial toxic substances. These substances, known as neurotoxins, can disrupt or kill neurons, the cells responsible for transmitting signals in the brain and other parts of the nervous system. This can lead to a range of symptoms, from cognitive impairments and motor dysfunction to severe neurological disorders.

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research 5α-reduced progestogens ameliorate mood-related behavioral pathology, neurotoxicity, and microgliosis associated with exposure to HIV-1 Tat

47 citations , January 2016 in “Brain Behavior and Immunity”

5α-reduced progestogens may reduce mood issues and brain damage linked to HIV-1 Tat.

Focal Neurotoxicity Associated With Topical 5-Fluorouracil

research Focal Neurotoxicity Associated With Topical 5-Fluorouracil

February 2024 in “Curēus”

Topical 5-Fluorouracil can rarely cause nerve damage, especially in people with a certain genetic deficiency.

Zizyphus Jujuba Protects Against Ibuprofen-Induced Nephrotoxicity in Rats

research Zizyphus jujubaprotects against ibuprofen-induced nephrotoxicity in rats

15 citations , September 2013 in “Pharmaceutical Biology”

Jujube fruit extract may reduce kidney damage from ibuprofen in rats.

Use of Mannitol Diuresis to Reduce Cisplatin Nephrotoxicity

research Use of Mannitol Diuresis to Reduce Cis-Platinum Nephrotoxicity

August 1978 in “Dicp-The annals of pharmacotherapy”

Mannitol diuresis allows higher doses of cis-platinum for testicular cancer treatment without increasing kidney damage.

research Hepato- and neuro-toxicity by ethylenthiourea.

2 citations , June 1985 in “PubMed”

Ethylenthiourea is toxic to the liver and nervous system, especially with alcohol.

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