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Anxiety and Depression-Like Behaviour Following Short-Term Finasteride Administration Is Associated With Impaired Synaptic Plasticity and Cognitive Behaviour in Male Rats

research Anxiety-, and Depression-like Behaviour Following Short-Term Finasteride Administration is Associated with Impaired Synaptic Plasticity and Cognitive Behaviour in Male Rats

April 2024 in “Journal of psychiatric research”

Short-term finasteride use in male rats caused anxiety, depression, and memory problems.

research 1442 Neurotransmitter signaling specify sweat gland stem cell fate through intracellular calcium regulation

April 2023 in “Journal of Investigative Dermatology”

PRP can improve hair growth in people with hair loss, but more research is needed.

research 176 Characterising Neurotransmitter Signalling in Human Skin and Hair Follicles

November 2024 in “Journal of Investigative Dermatology”

Skin and hair cells release serotonin and histamine naturally, which could help improve skin health.

research Gene polymorphisms and serum levels of BDNF and CRH in vitiligo patients

July 2022 in “PLOS ONE”

Certain gene variations and different levels of BDNF and CRH hormones are linked to vitiligo.

Neuroendocrine, Neurotransmitter, and Gut Microbiota Imbalance Contributing to Potential Psychiatric Disorder Prevalence in PCOS

research Neuroendocrine, Neurotransmitter, and Gut Microbiota Imbalance Contributing to Potential Psychiatric Disorder Prevalence in PCOS

September 2023 in “F&S reports”

PCOS may increase the risk of mental health issues like depression and anxiety.

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Community Join

5 / 36 results

community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.

in Research/Science 140 upvotes 2 years ago

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.

community How finasteride lowers brain's happiness steroid allopregnanolone and causes depression: systemic dihydroprogesterone crosses blood brain barrier, you don't even need finasteride and brain 5ar for that

in Finasteride/Dutasteride 286 upvotes 1 year ago

Finasteride may lower allopregnanolone levels, potentially affecting mood, but many users report improved mental health due to reduced hair loss. Experiences with finasteride and dutasteride vary, with some experiencing side effects and others finding them beneficial for hair retention and overall happiness.

community Another theory for hair loss: Parasites in gut.

in Research/Science 7 months ago

Parasites in the gut may contribute to hair loss by depleting essential nutrients and disrupting hormone balance. An imbalance of hormones, not just DHT, could be a factor in androgenic alopecia.

community Checking in with my post-fin symptoms

in Finasteride 5 upvotes 9 years ago

A user reports persistent sexual side effects three months after stopping finasteride, despite a healthy lifestyle and supplements. They express concern over the lack of libido and infrequent erections.

community Is it sufficient to block scalp DHT topically, or is it also necessary to reduce serum DHT? (My Question is Elaborated Below)

in Research/Science 17 upvotes 1 year ago

Topical finasteride can be as effective as oral finasteride for hair regrowth with fewer systemic side effects, but precise dosing is essential. Combining oral dutasteride with topical finasteride is not recommended due to dutasteride's stronger inhibition.

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