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research 877 Loss of UBE2N in keratinocytes leads to skin inflammation and immune infiltration through IRAK1/4-mediated processes

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Removing UBE2N from skin cells causes inflammation and immune response, which can be lessened with specific inhibitors.

research The Medical Treatment of Cicatricial Alopecia

46 citations , March 2006 in “Seminars in Cutaneous Medicine and Surgery”

Current treatments for cicatricial alopecia can manage symptoms but don't stop hair loss or the disease.

research A study of the histopathological features of alopecias on transverse sections of scalp biopsies

3 citations , January 2019 in “Indian Journal of Dermatology”

Transverse scalp biopsy sections help diagnose different alopecias by showing hair follicle details and inflammation patterns.

research Kava-induced acute cutaneous toxicity: An increasingly recognized characteristic clinicohistologic pattern

2 citations , November 2018 in “JAAD case reports”

Drinking kava tea can cause a skin reaction with red, swollen bumps, which may improve with steroids.

research Folliculitis Decalvans: An Uncommon Case Report with Review of Literature

January 2025 in “International Journal of Applied and Basic Medical Research”

Effective treatment of folliculitis decalvans requires accurate diagnosis and more research for better therapies.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community DHT Harms Scalp Microbiome: DHT Itch is REAL

in Research/Science 416 upvotes 1 year ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

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