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research 877 Loss of UBE2N in keratinocytes leads to skin inflammation and immune infiltration through IRAK1/4-mediated processes

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Removing UBE2N from skin cells causes inflammation and immune response, which can be lessened with specific inhibitors.

research The Medical Treatment of Cicatricial Alopecia

46 citations , March 2006 in “Seminars in Cutaneous Medicine and Surgery”

Current treatments for cicatricial alopecia can manage symptoms but don't stop hair loss or the disease.

research The histopathologic spectrum of psoriasis

111 citations , November 2007 in “Clinics in Dermatology”

Psoriasis skin changes are complex and might need several biopsies for a clear diagnosis.

research A study of the histopathological features of alopecias on transverse sections of scalp biopsies

3 citations , January 2019 in “Indian Journal of Dermatology”

Transverse scalp biopsy sections help diagnose different alopecias by showing hair follicle details and inflammation patterns.

research Dissecting Cellulitis of the Scalp

July 2018 in “Elsevier eBooks”

Early treatment is key to prevent permanent hair loss from scalp conditions that cause scarring.

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community DHT Harms Scalp Microbiome: DHT Itch is REAL

in Research/Science 416 upvotes 1 year ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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