The Hair Loss Encyclopedia

Search

for
Search:

Did you mean NFATc?

GlossaryNFATc1

protein regulating gene expression in immune and hair follicle cells

NFATc1, or Nuclear Factor of Activated T-Cells, cytoplasmic 1, is a protein that plays a crucial role in the regulation of gene expression in immune cells, particularly T-cells. It is involved in the activation of immune responses and has also been implicated in various biological processes, including the development and function of hair follicles.

Related Terms

Learn

0 / 0 results

— no results

Research

5 / 469 results

research Nfatc1 Balances Quiescence and Proliferation of Skin Stem Cells

415 citations , January 2008 in “Cell”

NFATc1 controls hair stem cell activity, affecting hair growth and could be a target for hair loss treatments.

Cyclosporin A-Induced Hair Growth in Mice Is Associated with Inhibition of Calcineurin-Dependent Activation of NFAT in Follicular Keratinocytes

research Cyclosporin A-Induced Hair Growth in Mice Is Associated with Inhibition of Calcineurin-Dependent Activation of NFAT in Follicular Keratinocytes

57 citations , June 2003 in “American Journal of Physiology-cell Physiology”

Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.

research NFAT5 Mediates Hypertonic Stress-Induced Atherosclerosis via Activating NLRP3 Inflammasome in Endothelium

50 citations , August 2019 in “Cell Communication and Signaling”

NFAT5 triggers atherosclerosis under stress by activating inflammation in blood vessels.

Calcineurin/NFATc1 Signaling Links Skin Stem Cell Quiescence to Hormonal Signaling During Pregnancy and Lactation

research Calcineurin/NFATc1 Signaling Links Skin Stem Cell Quiescence to Hormonal Signaling During Pregnancy and Lactation

40 citations , April 2014 in “Genes & Development”

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

research A New Role for an Old Friend: NFAT and Stem Cell Quiescence

4 citations , February 2008 in “Cell stem cell”

NFATc1 is crucial for keeping hair follicle stem cells inactive.

View more "nfat" in research →

Community Join

0 / 0 results

— no results