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research Dynamic Signals for Hair Follicle Development and Regeneration

60 citations , July 2011 in “Stem Cells and Development”

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

Double-Stranded RNA Induces Inflammation via the NF-κB Pathway and Inflammasome Activation in the Outer Root Sheath Cells of Hair Follicles

research Double-stranded RNA induces inflammation via the NF-κB pathway and inflammasome activation in the outer root sheath cells of hair follicles

22 citations , March 2017 in “Scientific reports”

Double-stranded RNA causes inflammation in hair follicle cells, which may help understand and treat alopecia areata.

research XEDAR activates the non-canonical NF-κB pathway

18 citations , August 2015 in “Biochemical and Biophysical Research Communications”

XEDAR triggers a specific signaling pathway in cells.

research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways

1 citations , May 2017 in “InTech eBooks”

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.