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      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

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      nucleoside used for hair regrowth stimulant properties

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      a synthetic estrogen used topically as an anti-androgen

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      commercial product with a blend of mostly natural ingredients for hair regrowth

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      community No progress from Feb 2025 to Jan 2026

      in Progress Pictures  9 upvotes 1 day ago
      The user has not seen significant progress in hair growth using topical minoxidil, finasteride, and biotin shampoo over a year. Suggestions include switching to dutasteride, adding microneedling, and considering other treatments like scalp massages and blood tests.

      community No results, still more hairloss

      in Finasteride/Dutasteride  16 upvotes 2 months ago
      The user experienced severe hair loss despite using Minoxidil and Finasteride and is considering switching to Dutasteride. Others recommend consulting a dermatologist, checking for health issues, and trying Dutasteride and oral Minoxidil.

      community No shedding but temples & frontal receeding

      in Finasteride/Dutasteride 3 months ago
      A 24-year-old male started using finasteride and minoxidil for hair loss, noticing reduced hair fall but continued temple and frontal recession. He uses both oral and topical minoxidil, biotin, vitamin D, and coal tar shampoo, and experiences rare heart palpitations.

      community No longer seeing any progress, really worried and panicking.

      in Progress Pictures  114 upvotes 3 months ago
      The user is experiencing increased hair thinning and shedding despite using oral dutasteride, oral minoxidil, topical dutasteride, and ketoconazole shampoo. Many recommend considering a hair transplant or embracing baldness, as current treatments seem ineffective.