Most nonbald men's multi-hairfollicles are naturally positioned perpendicular to a line from the scalp's crown, which is important for natural-looking hair transplants.
Most men's multi-hairfollicles naturally stand perpendicular to a line from the top of their head, which is important for natural-looking hair transplants.
Tretinoin can cause non-telogen hair loss in some men by inducing catagen-like changes in hairfollicles and through retinoid toxicity, especially when used with minoxidil. Some users report hair loss even when using retinoids on the face, while others experience benefits when combined with treatments like finasteride and minoxidil.
Ultrasound imaging can non-invasively detect active and inactive hairfollicles, inflammation, and fibrosis, potentially reducing unnecessary biopsies. It may help assess hair growth potential and diagnose scalp issues, but some users believe in trying treatments regardless of ultrasound results.
Some individuals do not respond to oral minoxidil for hair loss, despite it generally working by improving blood flow to hairfollicles. Factors like metabolism, drug interactions, and individual variations in the drug's activation may influence its effectiveness.
Balding scalps have more androgen receptors, leading to increased TGF-beta, which causes blood vessel loss and hairfollicle miniaturization. Blocking androgen signaling and TGF-beta may help prevent hair loss.
PP405 is anticipated as a future treatment for dormant hairfollicles, but its effectiveness and safety are uncertain. Current treatments include oral minoxidil and microneedling, with some avoiding finasteride due to side effects.