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Did you mean Non-Scarring Alopecia?

GlossaryNon-Scarring Alopecia

hair loss without permanent follicle damage, allowing potential regrowth

Non-Scarring Alopecia, also known as Non-Cicatricial Alopecia, refers to hair loss where the hair follicles are not permanently damaged, meaning the potential for hair regrowth remains. This type of hair loss can be caused by various factors such as hormonal changes, nutritional deficiencies, or autoimmune conditions like alopecia areata, and it contrasts with scarring alopecia, where hair follicles are irreversibly destroyed.

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research Stem cell markers (cytokeratin 15, CD34 and nestin) in primary scarring and nonscarring alopecia

54 citations , January 2009 in “British Journal of Dermatology”

Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.

research Nonscarring alopecia in systemic lupus erythematosus: A cross-sectional study with trichoscopic, histopathologic, and immunopathologic analyses

39 citations , May 2019 in “Journal of the American Academy of Dermatology”

Hair loss in lupus patients indicates higher disease activity.

research A case report of inflammatory nonscarring alopecia associated with the epidermal growth factor receptor inhibitor erlotinib

33 citations , June 2009 in “Journal of Cutaneous Pathology”

Erlotinib can cause nonscarring hair loss and itchy skin.

research Lipedematous alopecia: an uncommon clinicopathologic variant of nonscarring but permanent alopecia

30 citations , May 2008 in “International Journal of Dermatology”

Lipedematous alopecia causes permanent hair loss due to increased scalp fat.

research Quality of life and psychosocial impact of scarring and non‐scarring alopecia in women

28 citations , January 2015 in “Journal der Deutschen Dermatologischen Gesellschaft”

Women with scarring alopecia have a lower quality of life and more anxiety and depression than those with non-scarring alopecia.

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community Quote from Pelage (PP-405) Spokesperson...

in Research/Science 122 upvotes 9 months ago

Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

community scarring alopecia awareness in this community

in Chat 33 upvotes 3 years ago

Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

community Sexual Dysfunction in Those with Androgenetic Alopecia on Dutasteride Versus Finasteride

in Finasteride/Dutasteride 113 upvotes 1 year ago

Dutasteride and finasteride have similar risks of sexual dysfunction for treating androgenetic alopecia. Users experience varying side effects, indicating individual differences in drug reactions.

community Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men

in Research/Science 26 upvotes 4 years ago

N-Acetyl-Cysteine (NAC) was found to improve hair parameters in men with early-onset androgenetic alopecia, showing increased terminal hair count and decreased vellus hair count, with good tolerability. NAC, used alone or with minoxidil, may help due to its antioxidant properties, though its effectiveness can vary among individuals.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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