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research Non-canonical dimerization of the androgen receptor and other nuclear receptors: implications for human disease

25 citations , June 2019 in “Endocrine Related Cancer”

Mutations in certain receptors can cause diseases and offer new treatment options.

research Drug safety evaluation of exemestane

7 citations , March 2011 in “Expert Opinion on Drug Safety”

Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.

research Fulvestrant, a new treatment option for advanced breast cancer: tolerability versus existing agents

67 citations , October 2005 in “Annals of Oncology”

Fulvestrant is a well-tolerated new treatment for advanced breast cancer that may delay chemotherapy.

research Effects of aromatase inhibitors on human osteoblast and osteoblast-like cells: A possible androgenic bone protective effects induced by exemestane

50 citations , December 2006 in “Bone”

Exemestane may protect bones by stimulating osteoblast growth through androgen-related pathways.

research Botulinum Toxin Off-Label Use in Dermatology: A Review

53 citations , January 2017 in “Skin appendage disorders”

Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.

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Community Join

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community Finasteride doubled my testosterone & estrogen

in Chat 265 upvotes 8 months ago

Finasteride increased testosterone and estrogen, stopped hair loss, and promoted regrowth. Users discussed side effects like libido changes and considered adding minoxidil and aromatase inhibitors.

community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 194 upvotes 1 year ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.

community I always hear the advice to reduce scalp inflammation. What are some non-steroidal ways to reduce inflammation?

in Treatment 13 upvotes 1 year ago

Non-steroidal ways to reduce scalp inflammation include using topical melatonin, urea shampoo, Zyrtec, turmeric with black pepper, omega-3 supplements, a self-made topical solution with cetirizine, melatonin, and piroctone olamine, ketoconazole shampoo, witch hazel shampoo, tacrolimus, and lifestyle changes like a healthy diet and regular exercise. Some users also mentioned unconventional methods like infrared light therapy and a carnivore diet.

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