research Role of Aire and Notch4 Allelic Mutations in Alopecia Areata in C3H/HeJ Mice
Aire mutation reduces alopecia areata, while Notch4 mutation prevents it in mice.
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5 / 1000+ resultsresearch Impaired Notch-MKP-1 Signalling in Hidradenitis Suppurativa: An Approach to Pathogenesis by Evidence from Translational Biology
Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.
research Pleiotropic Role of Notch Signaling in Human Skin Diseases
Notch signaling disruptions can cause various skin diseases.
research Control of Hair Follicle Cell Fate by Underlying Mesenchyme Through a CSL–Wnt5a–FoxN1 Regulatory Axis
Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.
research Epigallocatechin-3 Gallate Inhibits STAT-1/JAK2/IRF-1/HLA-DR/HLA-B and Reduces CD8 NKG2D Lymphocytes in Alopecia Areata Patients
EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.
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5 / 64 resultscommunity Why the fu*k do people behave like this?
People making comments on others' hair loss, and the different strategies used to deal with it. Treatments mentioned include finasteride and minoxidil.
community 4 months of 1mg of fin a day and 5 months of topical minoxidil
Significant hair regrowth was achieved using 1mg of finasteride daily, 3ml of topical minoxidil, ketoconazole shampoo, vitamin D, and castor oil, with no side effects. Results appeared after two months, leading to discussions on treatment effectiveness and commitment.
community Had my 6 month checkup today and saw better results than I thought. More full up top and my facial hair has also gotten fuller as well
A user who has seen results of hair regrowth after 6 months of using finasteride 1.25mg daily, and topical foam minoxidil twice a day for 3 months before switching to once a day; other users have advised against increasing the dose of finasteride due to lack of additional scalp DHT reduction and increased risk of side effects.
community Shoutout to Zinc pyrithione and Piroctone olamine
Zinc pyrithione and piroctone olamine are effective for reducing hair shedding, possibly more so than ketoconazole. There is a concern about zinc pyrithione shampoo interfering with minoxidil, but it's unclear if this is proven.
community Front page article at The New York Times (biggest circulation in the world) regarding notable results with oral minoxidil is a pretty big deal
This conversation discusses the potential benefits of using oral minoxidil and finasteride to treat hair loss, with some users sharing their own experiences in taking the medications. Others express concerns about the safety of these treatments.