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GlossaryNude Mice

laboratory mice lacking a thymus, impairing their immune system

Nude mice, also known as athymic mice, are a type of laboratory mouse that lacks a thymus, resulting in an impaired immune system and an inability to produce T cells. This makes them valuable in scientific research, particularly for studying cancer, immunology, and for growing human tissues and tumors, as they do not reject foreign cells.

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Research

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research Failure of passive transfer of serum from patients with alopecia areata and alopecia universalis to inhibit hair growth in transplants of human scalp skin grafted on to nude mice

60 citations , February 1992 in “British Journal of Dermatology”

Serum from alopecia patients does not stop hair growth in grafted skin on mice.

research FOXN1 Is Critical for Onycholemmal Terminal Differentiation in Nude (Foxn1nu) Mice

58 citations , November 2004 in “The journal of investigative dermatology/Journal of investigative dermatology”

The Foxn1 gene is essential for normal nail and hair development.

research Cyclosporin A stimulates hair growth in nude mice.

55 citations , June 1987 in “PubMed”

Cyclosporin A significantly increases hair growth in certain areas of mice.

research Differences in activity of minoxidil and cyclosporin A on hair growth in nude and normal mice. Comparisons of in vivo and in vitro studies.

35 citations , January 1990 in “PubMed”

Cyclosporin A boosts hair growth in nude mice, but minoxidil does not.

research Reduced Linear Hair Growth Rates of Vellus and of Terminal Hairs Produced by Human Balding Scalp Grafted onto Nude Mice

23 citations , December 1991 in “Annals of the New York Academy of Sciences”

Balding scalps slow down hair growth.

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Community Join

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community Has anybody heard of this new cure?

in Treatment 2740 upvotes 7 months ago

A new hair loss treatment shows promise in mice but is unproven in humans. Effective treatments include finasteride and minoxidil.

community Shoutout to the mice that tested our Minoxidil

in Satire 147 upvotes 1 year ago

The conversation humorously acknowledges the role of mice in testing Minoxidil for hair loss while also discussing the ethics of animal testing. Some users argue against animal testing, citing cruelty, while others defend its necessity for medical advancements.

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Learn

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learn Overview

learn Thymosin Beta 4

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Clinics

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Trichology
Center Kosmetologii I Plasticheskoy Khirurgii Imeni S.v. Nudel'manaYekaterinburg · RU

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