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Research
5 / 1000+ resultsresearch Peptidylarginine Deiminase Isoforms Are Differentially Expressed in the Anagen Hair Follicles and Other Human Skin Appendages
PAD enzymes play a key role in hair growth and structure.
research Deimination in epidermal barrier and hair formation
Enzymes that change arginine to citrulline are important for skin barrier and hair formation, and their malfunction can lead to skin conditions and hair disorders.
research Evaluation of Patient with Peripheral Arterial Disease: General Surgeons’ Perspective
Peripheral arterial disease (PAD) is a growing global health concern, affecting over 200 million people, with a significant impact in India due to factors like aging, diabetes, and smoking. The shortage of vascular surgeons in India, particularly in rural areas, necessitates general surgeons to manage PAD diagnosis and treatment. Accurate diagnosis involves a comprehensive history and physical examination, with tools like the Ankle-Brachial Index (ABI) being crucial, though alternatives are needed for calcified vessels. Various diagnostic methods, including pulse volume recording, continuous-wave Doppler, and duplex ultrasound, are discussed, with catheter-based contrast angiography as the gold standard for imaging. The document emphasizes the importance of these diagnostic tools in guiding effective management strategies for PAD.
research Deimination and Peptidylarginine Deiminases in Skin Physiology and Diseases
PADs are crucial for healthy skin and hair, and their imbalance can cause skin and hair disorders.
research Genetic Susceptibility to Alopecia
Certain mutations in the PADI3 gene may increase the risk of developing a type of scarring hair loss common in women of African descent.
Community Join
5 / 1000+ resultscommunity Put P5P in my shampoo, reduced itch a lot!
The user added P5P (vitamin B6) to their shampoo to reduce scalp itch, which improved significantly. They have been using finasteride for hair loss but are exploring additional treatments like topical antiandrogens and prolactin inhibitors.
community P5P supplementation for fin sides.
P5P supplementation helped reverse finasteride side effects, particularly by lowering prolactin levels and restoring sensitivity. The user experienced significant improvement within a day and full recovery in a few days.
community Treating my DUPA via controlling inflammation
The user has DUPA and suspects autoimmune activity as a cause. They have tried various treatments including finasteride, minoxidil, dutasteride, pyrilutamide, estrogel, hydrocortisone, and clobetasol, and are now seeking a long-term immunosuppressant.
community Pp405 AAD presentation tomorrow - fingers crossed - what to expect?
New hair loss treatments PP405 and VDPHL01 are discussed with skepticism and hope, alongside existing treatments like minoxidil and finasteride. Users express frustration over limited progress since the 1980s but remain cautiously optimistic.
community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied
Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.