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GlossaryPathogenesis

process of disease development and progression in the body

Pathogenesis refers to the process by which a disease develops and progresses in the body. It involves understanding the initial cause of the disease, the sequence of events at the cellular and molecular levels, and how these events lead to the clinical symptoms observed. For example, in the context of alopecia, pathogenesis would explore how genetic, hormonal, and environmental factors contribute to hair loss.

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research Pathogenesis of acne vulgaris. I. Comedogenic properties of human sebum in external ear canal of the rabbit

98 citations , July 1968 in “Archives of Dermatology”

Human sebum can cause acne by clogging pores.

research Pathogenesis in Trichorrhexis Invaginata (Bamboo Hair)

72 citations , July 1984 in “Journal of Investigative Dermatology”

research Role of FGFR2-signaling in the pathogenesis of acne

63 citations , May 2009 in “Dermato-endocrinology”

Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.

research Pathogenesis of Hand-Foot Syndrome induced by PEG-modified liposomal Doxorubicin

63 citations , February 2013 in “Human cell”

PEGL-DOX causes Hand-Foot Syndrome due to skin reactions from prolonged circulation and ROS generation.

research Pathogenesis of Cardiovascular Alterations in Dogs Treated with Minoxidil

60 citations , January 1989 in “Toxicologic Pathology”

Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.

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community Proposed new pathogenesis model for androgenetic alopecia (AGA)

in Research/Science 7 upvotes 3 years ago

The conversation discusses a new model for understanding androgenetic alopecia (AGA), linking it to dietary and lifestyle factors similar to PCOS, and highlighting the role of DHT, vascular damage, and inflammation. Treatments mentioned include Minoxidil, finasteride, and RU58841.

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