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highly targeted anti-androgen that might have minimal systemic effects
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acid used for antimicrobial, anti-inflammatory and anti-androgenic properties
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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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research Pathways to inflammation: acne pathophysiology
Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.
research Acne scars: Classification and treatment
The book concludes that treating acne scars requires a variety of methods and patience, with no single best way to classify or treat them.
research Polymorphisms in Genes Involved in Steroidogenesis in the Development of Severe Acne
Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.
research Pathophysiology, diagnosis and treatment of polycystic ovary syndrome
The document concludes that PCOS is a complex condition that can reduce fertility and affect self-esteem, but it can be managed with various treatments.
research Pathophysiology of Insulin Resistance and Related Skin Diseases ( Review Article)
Insulin resistance can lead to skin problems like acne and psoriasis.
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5 / 21 resultscommunity Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?
The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.
community How do we only have two treatments to combat hair loss at this point in time?
The post discusses frustration over the limited and not always effective treatments for hair loss, mainly Minoxidil and Finasteride. The conversation includes mentions of potential new treatments like GT20029, HMI-115, CosmeRNA, KX-826, and microneedling, but also highlights the challenges of funding and prioritizing research in this area.
community dut doomers - any photo evidence of people regrowing AFTER going back to fin?
Some users experience worsening hair loss with dutasteride and improvement after switching back to finasteride, while others find better results with dutasteride. The effectiveness of treatments like finasteride, dutasteride, minoxidil, and RU58841 varies, requiring individuals to try different combinations or dosages to find what works best.
community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied
Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance
The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.