Search

for
Search:

Did you mean PDE4 inhibitors?

GlossaryPDE4 inhibitors

block an enzyme to reduce inflammation and immune responses

PDE4 inhibitors, also known as Phosphodiesterase 4 inhibitors or PDE4i, are a class of drugs that block the enzyme phosphodiesterase 4. This enzyme is involved in breaking down cyclic adenosine monophosphate (cAMP), a molecule that plays a crucial role in regulating inflammation and immune responses. By inhibiting PDE4, these drugs can help reduce inflammation and are used to treat conditions like psoriasis, chronic obstructive pulmonary disease (COPD), and certain types of alopecia.

Related Terms

Learn

0 / 0 results

— no results

Research

5 / 388 results

Systematic Review of Newer Agents for the Management of Alopecia Areata in Adults: Janus Kinase Inhibitors, Biologics and Phosphodiesterase-4 Inhibitors

research Systematic Review of Newer Agents for the Management of Alopecia Areata in Adults: Janus Kinase Inhibitors, Biologics and Phosphodiesterase-4 Inhibitors

12 citations , December 2022 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

New oral treatments for adult hair loss show promise, especially JAK inhibitors, with mild side effects.

research Apremilast Treatment of Atopic Dermatitis and Other Chronic Eczematous Dermatoses

31 citations , July 2017 in “Journal of the American Academy of Dermatology”

Apremilast improved symptoms in patients with severe skin conditions.

Targeting Anti-Inflammatory Immunonanocarriers to Human and Murine Neutrophils via Ly6 Antigen for Psoriasiform Dermatitis Alleviation

research Targeting Anti-Inflammatory Immunonanocarriers to Human and Murine Neutrophils via Ly6 Antigen for Psoriasiform Dermatitis Alleviation

April 2023 in “Journal of Investigative Dermatology”

The study created special nanoparticles that effectively deliver an anti-inflammatory drug to treat skin inflammation in psoriasis.

research Non-FDA-Approved Uses of Apremilast in Dermatology: A Review of Current Available Literature

1 citations , September 2022 in “Nepal journal of dermatology, venereology & leprology”

Apremilast shows promise for several skin conditions but needs more research.

research Treatment of Alopecia Areata and Its Numerous Possibilities: A Literature Review

October 2024 in “Journal of Education Health and Sport”

Alopecia areata treatment should be personalized, using topical or systemic therapies based on severity, with promising options like JAK inhibitors needing more research.

View more "pde-4 inhibitor" in research →

Community Join

5 / 7 results

community Ketocanzole 2% has almost completely recovered my hair loss

in Ketoconazole 327 upvotes 1 month ago

Ketoconazole 2% shampoo effectively regrew hair by treating scalp dermatitis and inflammation. The user also used jojoba and oat oil, Aveeno moisturizer, and hyaluronic acid for scalp care.

community Just started ru58841, ask me anything.

in Research/Science 14 upvotes 1 day ago

The conversation discusses a hair loss treatment regimen including oral dutasteride, oral minoxidil, tadalafil, and the recent addition of RU58841. The user shares experiences with these treatments, noting significant hair regrowth and stabilization, and discusses the cost and preparation of RU58841.

community 5mg cialis daily to deal with dutasteride

in Finasteride/Dutasteride 71 upvotes 3 weeks ago

Cialis is used to manage erectile dysfunction caused by finasteride and dutasteride, with mixed results. Some users report improvement, while others consider stopping the medication due to side effects.

community Told my gf I was considering getting back on finasteride

in Finasteride/Dutasteride 2997 upvotes 3 months ago

A user considered restarting finasteride for hair loss despite past side effects, which worried their girlfriend. Others suggested alternatives like topical treatments or lower doses and emphasized prioritizing well-being and relationship stability.

community What is the ultimate hair regrowth protocol

in Treatment 29 upvotes 5 months ago

The conversation covers aggressive hair regrowth treatments like Dutasteride, Minoxidil (oral and topical), RU58841, microneedling, and ketoconazole shampoo. It also mentions PRP, laser therapy, GHK-Cu injections, and hormone therapy for maximum regrowth.

View more "pde-4 inhibitor" in community →