Search
for

    Did you mean PDE4 inhibitors?
    GlossaryPDE4 inhibitors

    block an enzyme to reduce inflammation and immune responses

    PDE4 inhibitors, also known as Phosphodiesterase 4 inhibitors or PDE4i, are a class of drugs that block the enzyme phosphodiesterase 4. This enzyme is involved in breaking down cyclic adenosine monophosphate (cAMP), a molecule that plays a crucial role in regulating inflammation and immune responses. By inhibiting PDE4, these drugs can help reduce inflammation and are used to treat conditions like psoriasis, chronic obstructive pulmonary disease (COPD), and certain types of alopecia.

    Related Terms

    Learn

    5 / 801 results

    Research

    5 / 486 results

    Community Join

    5 / 8 results

      community Hair Loss “Cure” for Inflammation: Topical Roflumilast

      in Research/Science  32 upvotes 2 months ago
      Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

      community Just started ru58841, ask me anything.

      in Research/Science  14 upvotes 2 months ago
      The conversation discusses a hair loss treatment regimen including oral dutasteride, oral minoxidil, tadalafil, and the recent addition of RU58841. The user shares experiences with these treatments, noting significant hair regrowth and stabilization, and discusses the cost and preparation of RU58841.

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  417 upvotes 11 months ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.